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USP12 inhibits T cell activation. 1 / 1

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"Thus, USP12 and OTUD7B counterbalance inhibitory E3 ligases to stabilize TCR signaling.Aside from acting at the proximal signalosome, E3 ligases also inhibit T-cell activation by acting further downstream, controlling the key transduction events that lead to the nuclear translocation of the T-cell activating transcription factors."

| PMC

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IndraLab

Statements

USP12 inhibits T cell activation. 1 / 1

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