IndraLab

Statements



sparser
"It has not been established which receptors mediate the central α-MSH-induced inhibition of peripheral inflammation."

reach
"A-MSH has been shown to inhibit the acute inflammation induced in mice by IL-1, IL-6 and TNF-a [41]."

sparser
"The α-MSH peptides inhibit acute inflammation induced in mice by rIL-1β ( Hiltz et al., 1992 )."

sparser
"Α-MSH inhibits inflammation in experimental autoimmune uveitis (EAU), induces CD25+ regulatory CD4+ T-cells [ xref , xref , xref ] and regulates ubiquitination in T cells as well [ xref ]."

reach
"The neuropeptide aMSH, a potent modulator of fever and inflammation, can act at the central level to inhibit inflammation in peripheral tissues (7)."

sparser
"Of note, inhibition of allergic airways inflammation in mice by α-MSH, is mediated via IL-10 production, because IL-10 knockout mice are resistant to α-MSH treatment ( Raap et al , 2003 )."

sparser
"Α-MSH can also inhibit the local inflammatory response by inhibiting neutrophil chemotaxis ( xref , xref )."

reach
"We conclude that a-MSH treatment suppressed inflammation and was associated with decreased expression of Th1 cytokines."