IndraLab

Statements

Barium(2+) inhibits NFKBIA. 5 / 5
| 5
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"IKBa demonstrated strong inward rectification and was inhibited by Ba (2+) in a dose- and voltage dependent fashion, with the K (d) decreasing with hyperpolarization."
17091215
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"BA further increased phospho-IkappaBalpha and phospho-p65 and decreased total IkappaBalpha compared to 2ME2 or Doc alone in LN-AI and DU145 cells, suggesting enhancement of NF-kappaB activity."
20618955
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"BA also downregulated the transcription of vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-beta) and decreased the expression of the NF-kB pathway proteins (NF-kB-P65, IkBalpha, and IKKalpha and beta) in the TNF-alpha-stimulated RA-FLS."
32718263
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"Both BA forms induced IkappaBalpha degradation, indicative of NF-kappaB activation, to comparable extents (XREF_FIG)."
28400473
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"BA suppressed the activation of IkappaBalpha kinase, thus abrogating the phosphorylation and degradation of IkappaBalpha."
12960358