IndraLab

Statements

TP53 binds BAP1. 9 / 9
2 | 7
sparser
"Mutual exclusivity of genomic alterations was also shown for TP53:IDH1 , IDH1: Kirsten rat sarcoma virus ( KRAS ), TP53:BAP1 , and IDH1:FGFR2 ."
41647590
sparser
"They also reported a tendency toward mutual exclusivity between multiple genes including TP53:IDH1, IDH1:KRAS, TP53:BAP1, and IDH1:FGFR2."
35321284
sparser
"Concurrent mutations in BAP1 and TP53 were associated with adverse outcome, with similar effects observed for acquired alterations in either of the two genes alone ( xref )."
30416077
sparser
"Mutations in BAP1 ( q = 0.004) and TP53 ( q = 0.001) were associated with decreased CSS in a multivariable model; only TP53 ( q = 0.005) remained significant when SSIGN score was included."
28753773
sparser
"Only three of the total 39 interactions— NF2-TP53 , NF2-SMAD4 , and BAP1-TP53 —commonly occurred in all three networks; 12 interactions were shared by only two of the networks and 24 were unique to specific networks ( xref )."
34561273
sparser
"On analyses adjusted only for cohort, we found that mutations in BAP1 ( n = 1049 for analysis; hazard ratio [HR]: 2.10; 95% confidence interval [CI]: 1.44–3.04; q < 0.001) and TP53 ( n = 784 for analysis; HR: 2.63; 95% CI: 1.36–5.08; q = 0.028) were significantly associated with increased risk of death from cancer after adjustment for multiple comparisons using competing risks regression ( xref )."
28753773
biogrid
No evidence text available
35446349
sparser
"Only BAP1 and TP53 were significantly associated with an inferior OS ( P  = 0.0002; P  = 0.0082)."
39123175
biogrid
No evidence text available
35584569