IndraLab

Statements

BC-1471 inhibits STAMBP. 2 / 2

| 2

reach

"As STAMBP activity is specific for K63 linked ubiquitin XREF_BIBR, BC-1471 inhibition of STAMBP mediated cleavage of K63 linked di-Ub demonstrates physiologically relevant target validation for our compound."

28492230

➶

reach

"BC-1471 inhibited the activity of STAMBP to cleave recombinant di-Ub in a concentration dependent manner with an half-maximal inhibitory concentration (IC 50) of 0.33 muM (0.09-1.21 muM; XREF_FIG)."

28492230

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IndraLab

Statements

BC-1471 inhibits STAMBP. 2 / 2

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