IndraLab

Statements

USP28 deubiquitinates SOX9. 2 / 2
| 2
reach
"Overexpression of WT USP28, but not its catalytically inactive form (USP28 ) or the ΔUSP truncation mutant (USP28 ), induced SOX9 deubiquitination and inhibited its degradation."
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reach
"In contrast, overexpression of USP28, but not its inactive form or ΔUSP truncation, led to decreased ubiquitination of SOX9 (Fig. 4B), suggesting that the catalytic activity of USP28 is essential for SOX9 deubiquitination."
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