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Reactive Oxygen Species inhibits USP22. 2 / 2

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"Whereas, in p53-deficient CRC cells, relief of ROS-mediated USP22 repression promotes FASN stabilization and lipid accumulation, and thus promotes tumorigenesis (Fig. 7D)."

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"Whereas, in p53-deficient CRC cells, ROS-mediated inhibition of USP22 is relieved, leading to FASN stabilization, which thus promotes lipid synthesis and tumor growth."

36333288

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Reactive Oxygen Species inhibits USP22. 2 / 2

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