IndraLab

Statements

Butyric acid inhibits STAT1. 7 / 10
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"This effect begins after 12 hours of treatment, indicating that the butyrate induced STAT1 loss is most likely an indirect effect."
24810717
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"ATRA as well as PMA abolished the degradation of STAT1 by butyrate but not by staurosporine, indicating that differentiation specifically desensitizes cells against butyrate."
24810717
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"Whereas butyrate reduces STAT1 in leukemia cells, most solid tumor derived cells show an induction of STAT1 after treatment (XREF_SUPPLEMENTARY)."
24810717
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"Butyrate effectively inhibited IFN-gamma-induced STAT1 activation, resulting in inhibition of iNOS upregulation in human colon epithelial and carcinoma cells in vitro."
22517765
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"Furthermore, butyrate suppressed IFN-gamma-mediated inflammation in colon epithelial cells by preventing STAT-1 activation and blocking iNOS induction [XREF_BIBR]."
24876678
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"We did some additional tests to clarify whether other proteases contribute to the degradation of STAT1 in NB4 cells treated with butyrate."
24810717
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"Butyric acid was also demonstrated to effectively inhibit STAT1 activation by reducing IFN-gamma production, which results in the apoptosis of T cells of unspecified type and the suppression of the inflammation [XREF_BIBR]."
28702095