IndraLab

Statements

USP25 decreases the amount of IFNB1. 3 / 3
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"Taken together, our results suggest that USP25 negatively regulates IFN-beta expression by inhibiting SEV induced activation of IRF3 and NF-kappaB."
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"We found that knockdown of Usp21 in mouse fibroblast L929 cells significantly enhanced the expression of Ifnb, Ifna4, and Isg15 (XREF_FIG)."
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"Our data showed that Usp21 knockdown significantly enhanced Ifnb expression in WT but not in Sting -/- MEFs (XREF_FIG)."
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