IndraLab

Statements

USP18 activates AKT. 7 / 7
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"Tan et al. have demonstrated that USP18 promotes breast cancer growth by upregulating EGFR and activating the AKT and Skp2 pathway."
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"For instance, Tan et al. found that USP18 promotes breast cancer growth by upregulating EGFR and activating the AKT and Skp2 pathway [XREF_BIBR]."
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"In malignant tumors, USP18 is elevated and activates AKT/mTOR signaling, promotes phosphorylated AKT (p-AKT) and p-mTOR protein expression, leading to cancer cell proliferation and migration (106)."
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"In conclusion, USP18 promoted the proliferation and migration of ovarian cancer cells by activating AKT/mTOR signaling."
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"USP18 contributes to the proliferation and migration of ovarian cancer cells by regulating the AKT/mTOR signaling pathway."
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"USP18 promotes breast cancer growth by upregulating EGFR and activating the AKT and Skp2 pathway."
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"For instance, USP18 promotes breast cancer growth by upregulating EGFR and activating the AKT/Skp2 pathway [ 12 ]."
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