IndraLab

Statements


USP29 activates CLSPN. 2 / 3
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"A recent report indicates that USP29 promotes CLASPIN (not CHK1) stability, ensuring CHK1 activation in response to UV irradiation."

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"The deubiquitinases USP9X and USP29 promote Claspin stabilization during the S phase, and thus, adequate replication fork progression, by opposing its proteasomal degradation [23,24]."