IndraLab

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YOD1 activates cell population proliferation. 18 / 18
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"YOD1 promoted the proliferation of hepatocytes and led to hepatomegaly depending on the YAP/TAZ activity [36]."
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"YOD1 overexpression promotes TNBC cell proliferation, migration and invasion."
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"Using a transgenic mouse model, we confirmed that the Dox inducible expression of YOD1 in the liver enhanced the proliferation of hepatocytes, and led to hepatomegaly in a YAP and TAZ-activity-dependent manner."
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"In the present study, we have shown that knockdown of YOD1 by siRNA inhibited proliferation and migration of HOK cells in vitro."
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"We provide evidence for the first time that YOD1 contributes to changing the abilities of cell proliferation and migration regulated by TGF-β3 signaling pathway, which may be involved in the pathogenesis of NSCL/P.We explored the effects of YOD1 siRNA on the proliferation and migration of HOK cells."
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"The CCK-8 assay showed that knockdown of YOD1 by siRNA inhibited the HOK cells proliferation."
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"However, a recent study showed that downregulation of YOD1 may promote cell proliferation in cervical cancer cells [28]."
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"EDU and Flow Cytometry showed that high expression of YOD1 could significantly promote the proliferation of PAAD cells."
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"Consistent with previous studies, we showed that overexpression of YOD1 enhanced osteosarcoma progression, including elevated cell proliferation, cell adhesion and inhibited cell apoptosis."
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"Several studies showed that YOD1 induced cancer progression by upregulating cell proliferation and inhibiting cell apoptosis partly via Yes Associated Protein 1 (YAP) signaling, such as liver cancer [[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"These results indicate that silencing YOD1 in APL cells can suppress cell proliferation, induce cell apoptosis and cell differentiation in a PML/RARα-dependent manner.Next, to confirm that YOD1 could be an effective therapeutic target in AML, we evaluated the effect of YOD1 inhibition on normal human hematopoietic stem cells (HSCs)."
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"Using a transgenic mouse model, we showed that the inducible expression of YOD1 enhances the proliferation of hepatocytes and leads to hepatomegaly in a YAP and TAZ-activity-dependent manner."
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"For example, YOD1 enhanced the proliferation of hepatocytes and led to hepatomegaly via YAP/TAZ signaling, and upregulated YOD1 and YAP expression were observed in liver cancer patients [ 15 ]."
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"Inhibition of Cell Proliferation by YOD1 siRNA."
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"Interestingly, the inducible expression of YOD1 enhances the proliferation of hepatocytes and leads to hepatomegaly in a YAP and TAZ-activity-dependent manner."
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"Using a transgenic mouse model, we demonstrate that the inducible expression of YOD1 enhances the proliferation of hepatocytes and leads to hepatomegaly in a YAP and TAZ-activity-dependent manner."
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"Knockdown of YOD1 effectively inhibited TNBC cell migration, proliferation, cell cycle and resistance to cisplatin and paclitaxel."
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"We have shown that knockdown of YOD1 by RNAi inhibits the proliferation and migration of human oral keratinocytes (HOK) cells."
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