IndraLab

Statements


MSRA activates COPS5. 2 / 2
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"To investigate the possibility that MsrA activates Jab1 function, we followed the abundance of deneddylated Cul-1 (a substrate of Jab1) as function of the presence or absence of MsrA in mouse brain and liver extracts."

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"Furthermore, the ability of MsrA to increase Jab1 function (presumably through the reduction of critical MetO residue/s of Jab1) was further supported by the increase of deneddylation of Cul-1 in WT in comparison to MsrA KO brains (XREF_FIG)."