IndraLab

Statements


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sparser
"Combined with the inhibition of membrane-bound TGF-β1 by NRP2 targeting siRNA ( xref ), these results supported the hypothesis of a direct binding activity of TGF-β1 by NRP2 leading to smad2/3 phosphorylation in colorectal cancer cells."

sparser
"The group used surface plasmon resonance to demonstrate that NRP2 binds to TGFβ1 and performed co-immunoprecipitation to show that NRP2 complexes with TGFBR1 in HT29 cells."

reach
"To examine if NRP2 could directly bind active TGF-beta1, we studied the binding of TGF-beta1 to NRP2-Fc by Surface Plasmon Resonance (SPR)."

sparser
"Moreover, NRP2 expression was associated with an increase of TGF-β1 on HT29 cytoplasmic membrane, while treatment of Colo320 with NRP2-siRNA decreased membrane-bound TGF-β1 ( xref )."

sparser
"To examine if NRP2 could directly bind active TGF-β1, we studied the binding of TGF-β1 to NRP2-Fc by Surface Plasmon Resonance (SPR)."

sparser
"Together, these data suggest that NRP2 expression associates with less-differentiated high-grade tumors and TGF-β1 expression in HCC patients."