
IndraLab
Statements
reach
"As can be seen in XREF_FIG in both the HeRG stable cell line transfected with siRNA to deplete THOC1 (XREF_FIG) and in HeTH4 cells (+ DOX) transfected with the pIREC system (XREF_FIG), the spontaneous recombination frequency increased with respect to their respective controls, consistent with an increase in DNA breaks and subsequent recombination events taking place upon THO depletion."