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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 inhibits homeostatic process. 2 / 2

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"Novel oncogenic mutations in the TP53, BRCA2, PTEN, IL7R, RAS, NOTCH1, ETV6, BCL11B, WT1, DNMT3A, PRC2, PHF6, USP7, KDM6A and an array of other genes disrupt the genetic and epigenetic homeostasis in T-ALL."

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"XREF_BIBR, XREF_BIBR Indeed, recent findings suggest that haploinsufficiency or duplications of HAUSP disrupt neuronal homeostasis, giving rise to neurological and behavioral abnormalities, such as seizures, aggressiveness, hypotonia, intellectual disability, hypogonadism with clinical features of autism spectrum disorder and a condition similar to Schaaf-Yang syndrome."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...