IndraLab

Statements


Mutated BAP1 inhibits cytokine production. 3 / 3
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"BAP1 mutations inhibited the NF-kappaB signaling pathway, suppressing the cytokine secretion and antigen presentation by macrophages."

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"BAP1 mutations inhibited cytokine secretion and antigen presentation by macrophages."

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"BAP1 mutations may inhibit the NF-kappaB signaling pathway, repressing the cytokine secretion and antigen presentation by macrophages, which induces the immunosuppressive microenvironment, enhances the malignant phenotypes of UM cells and ultimately promotes the growth and metastasis of UM."