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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MIR375 inhibits USP1. 2 / 2

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"Further experiments revealed that up-regulated miR-375 expression led to USP1 down-regulation , and miR-375 overexpression suppressed PI3K / Akt signaling and inhibited NPC cell migration and invasion , but promoted NPC cell apoptosis ."

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"The luciferase assay confirmed miR-375 binding to the USP1 3 ' - untranslated region ( UTR ) , while the transfection experiment confirmed miR-375 expression reduced USP1 expression ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...