IndraLab

Statements


COPS6 decreases the amount of NKX2-2. 3 / 3
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"As showed in Fig. 5 H, overexpression of CSN6 reduced the ubiquitination level of Nkx2.2."

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"But, inhibition of CSN6 increased the ubiquitination level of Nkx2.2 ( Fig. 5 I )."

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"Moreover, we found that CSN6 inhibited SIRT2 expression by stabilizing the expression of Nkx2.2, a transcription factor which suppressed SIRT2 transcription [ 24 ]."