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Amodiaquine activates TP53. 1 / 2

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"Moreover, chloroquine, quinacrine, and amodiaquine trigger p53 stabilization in TP53-specific reporter human cancer cells and block the p53 ubiquitination properties of human double minute 2 (Hdm2) molecules, which in turn prevents p53 proteasome degradation."

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Amodiaquine activates TP53. 1 / 2

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