IndraLab

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USP8 activates ferritin. 2 / 2

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"We assumed that the regulation of ferritin mediated by USP8 is an autophagy-related process."

37051673

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"Taking all these data into consideration, we conclude that SQSTM1 acts as a platform, tethering NCOA4 to LC3 during the process of ferritinophagy.In summary, we report that USP8 inhibition promotes ferroptosis by promoting ferritin degradation in cancer cells."

37051673

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IndraLab

Statements

USP8 activates ferritin. 2 / 2

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