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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP14 activates CCNB1. 2 / 2

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"The resulting conjugates were incubated with purified human proteasomes that were washed with high salt to eliminate USP14, a deubiquitinating enzyme that can antagonize cyclin B1 degradation in vitro XREF_BIBR, XREF_BIBR."

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"Similarly, addition of an inhibitor of USP14, IU1, failed to accelerate degradation of cyclin B1 in Xenopus extracts (XREF_SUPPLEMENTARY)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...