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Rottlerin inhibits MAPK8. 2 / 4

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"Rottlerin, a specific inhibitor of PKC delta, significantly inhibited H (2) O (2)-induced activation of JNK1 in control cells, indicating that PKC delta is involved in the pathway."

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"In contrast, rottlerin inhibited PRAK and MAPKAP-K2, produced a substantial inhibition of JNK1α1, MSK1, PKA, PDK1, PKB/AKT, and GSK3β as well as non-kinase enzymes, including β-lactamase, α-chymotryps[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Rottlerin inhibits MAPK8. 2 / 4

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