IndraLab

Statements

Isotretinoin inhibits JUN. 10 / 10
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"A novel mechanism of action for v-ErbA : abrogation of the inactivation of transcription factor AP-1 by retinoic acid and thyroid hormone receptors."
1682056
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"A novel mechanism of action for v-ErbA : abrogation of the inactivation of transcription factor AP-1 by retinoic acid and thyroid hormone receptors."
7903219
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"A novel mechanism of action for v-ErbA : abrogation of the inactivation of transcription factor AP-1 by retinoic acid and thyroid hormone receptors."
8453668
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"Our previous studies in ferrets (Mustela putorius furo), an excellent model for studying carotenoid absorption and metabolism, showed that cigarette smoke exposure decreased levels of retinoic acid and retinoic acid receptor beta (RARbeta) protein, but increased levels of c-Jun and cyclin D1 proteins, and induced precancerous lesions in lung tissue [XREF_BIBR, XREF_BIBR]."
21665318
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"More specifically, retinoic acid or retinoic acid analogs are able to inhibit ATF2 [XREF_BIBR] and c-Jun [XREF_BIBR]."
26516076
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"Desbois C., Aubert D., Legrand C., Pain B. and Samarut J. : A novel mechanism of ~ Lction for v-erbA : abrogation of the inactivation of transcription factor AP-1 by retinoic acid and thyroid hormone [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
7734399
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"A novel mechanism of action for v-ErbA : abrogation of the inactivation of transcription factor AP-1 by retinoic acid and thyroid hormone receptors."
8324824
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"Lee and colleagues demonstrated in vitro that retinoic acid inhibited Jun N-terminal kinase (JNK), which phosphorylates and thus activates c-Jun, and that the inhibitory effect of retinoic acid on JNK activity was through the induction of mitogen activated protein (MAP) kinase phosphatase 1 (MKP-1) [XREF_BIBR, XREF_BIBR]."
21665318
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"In addition, we show that IL-1 and 12-O-tetradecanoyl-phorbol-13-acetate transiently induce c-jun and c-fos expression and that retinoic acid inhibits IL-1 and 12-O-tetradecanoyl-phorbol-13-acetate induction of c-fos, but not c-jun."
2178224
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"Endocrinology 114, 293-295 11 Desbois C, Aubert D, kegrand C, Pain B, Samarut J (1991) A novel mechanism of action of v-ErbA : Abrogation of the inactivation of transcription factor AP-1 by retinoic a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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