IndraLab

Statements

EIF3H inhibits translation. 3 / 3
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"Additionally, mHTT interacts with proteins involved in protein translation, such as Mapk3, Eif3h, and Eef1a2, potentially disrupting the protein translation process [80]."
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"We next tested the functional interaction between METTL3 and eIF3h, and found depletion of eIF3h abrogated the enhanced translation by METTL3 (XREF_FIG and XREF_FIG)."
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"They demonstrated that circLPAR1 encapsulated in exosomes could be internalized by colorectal cancer cells, and further suppressed tumour growth by directly bound with eukaryotic translation initiation factor 3 subunit h (eIF3h), suppressing the methyltransferase-like 3 (METTL3)-eIF3h interaction and decreasing the translation of oncogene bromodomain containing 4 [44]."
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