IndraLab

Statements


MiR-3940-5p decreases the amount of USP28. 2 / 2
| 2

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"As illustrated in XREF_FIG, A-D, compared with control cells, CCND1 and USP28 are downregulated at both mRNA and protein levels by ectopic expression of miR-3940-5p; however, pcDNA-CCND1 and pcDNA-USP28 robustly overturn this decreased expression of CCND1 and USP28 induced by miR-3940-5p."

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"In addition, a significant negative correlation was found between expressions of miR-3940-5p versus CCND1 mRNA (r = -0.794; XREF_FIG D) and USP28 mRNA (r = -0.709; XREF_FIG E), indicating that miR-3940-5p either directly or indirectly suppressed CCND1 and USP28 transcript levels."