IndraLab

Statements

USP47 binds XIAP. 6 / 6
2 | 2 2
reach
"We found that TLE3 inhibited the interaction between USP47 and XIAP, suggesting that TLE3 and USP47 compete for binding to XIAP and that the three proteins do not form a heterotrimeric complex (Fig. 4D, S7A)."
36749823
reach
"We show that although XIAP, USP47, and TLE3 can form dimeric complexes with one another, they are unable to form a stable trimeric complex."
36749823
sparser
"We found that TLE3 inhibited the interaction between USP47 and XIAP, suggesting that TLE3 and USP47 compete for binding to XIAP and that the three proteins do not form a heterotrimeric complex ( xref , xref )."
36749823
biogrid
No evidence text available
36749823
biogrid
No evidence text available
36749823
sparser
"Furthermore, we cannot distinguish whether XIAP and USP47 have overlapping binding sites on TLE3 or whether the binding of XIAP or USP47 induces a conformational change in TLE3 that precludes the binding of USP47 or XIAP, respectively."
36749823