IndraLab

Statements


SOX9 increases the amount of USP47. 3 / 3
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"Sox9 then migrates to the nucleus and upregulates the expression of USP47, which hampers the ubiquitination of Snail, thereby preventing the proteasomal degradation of Snail."

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"Furthermore, the silencing of Sox9 suppressed the expression of USP47 protein and manifestation of EMT."

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"Sox9 induces expression of USP47 by binding to its promoter region under hypoxic conditions."