IndraLab

Statements

USP19 activates cell death. 2 / 2
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"Based on these observations, we hypothesised that USP19 promotes BC cell death."
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"This indicates that the 494–1318 domain of USP19 contains the essential functional properties for misfolded TDP-43 secretion.To ensure that the observed secretion of misfolded TDP-43 was not simply the reflect of cell death potentially induced by the combined expression of USP19-WT and TDP-43-K263E, we assessed cell viability using the trypan blue exclusion method."
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