IndraLab

Statements

YOD1 inhibits MAVS. 6 / 6
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"The deubiquitinase YOD1 also antagonizes MAVS aggregation by cleaving K63-linked poly-Ub chains on MAVS [57]."
39193925
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"Subsequently, YOD1 removes the K63 linked ubiquitin chain and abrogates the aggregation of MAVS, thus inhibiting not only IRF3 and p65 activation, but also IFN-beta production."
33511009
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"Our previous studies have demonstrated that YOD1 negatively regulated RIG-I-mitochondrial antiviral signaling protein (MAVS) signaling during RNA virus infection."
38789414
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"YOD1 suppressed MAVS aggregation through cleaving the K63-linked ubiquitination, which led to reduced IFN-β production and cellular antiviral response [34]."
38789414
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"The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63 Linked Deubiquitination."
30952814
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"Distinguishing from the above E3s, YOD1 suppress MAVS aggregation through Lys63-linked deubiquitination (97)."
37901251