IndraLab

Statements


YOD1 inhibits MAVS. 2 / 2
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"The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63 Linked Deubiquitination."

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"Subsequently, YOD1 removes the K63 linked ubiquitin chain and abrogates the aggregation of MAVS, thus inhibiting not only IRF3 and p65 activation, but also IFN-beta production."