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USP8 inhibits MHC-I. 2 / 2

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"Another study demonstrated that MHC-I was upregulated by inhibition of the deubiquitinase USP8, through activation of the NF-κB pathway."

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"In addition , USP8 inhibition also triggers innate immune response and MHC-I expression largely through activating the NF-kappaB signaling ."

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IndraLab

Statements

USP8 inhibits MHC-I. 2 / 2

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