IndraLab

Statements



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"Moreover, N-6-methyladenosine (m6A) and pseudouridine within a polyU/UC RNA domain of hepatitis C virus were tested for cytosolic RIG-I stimulation and showed to reduce RIG-I signaling."

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"Additionally, the presence of m 6 A and pseudouridine in viral RNA was recently shown to attenuate the activation of the RIG-I innate signaling pathway."

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"In addition, abundant cellular RNAs, such as tRNAs and rRNAs, are extensively modified with unusual bases, such as pseudouridine, which prevent the activation of RIG-I and MDA5 (Ref."

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"Moreover, N-6-methyladenosine (m6A) and pseudouridine within a polyU/UC RNA domain of hepatitis C virus were tested for cytosolic RIG-I stimulation and showed to reduce RIG-I signaling."

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"Additionally, the presence of m6A and pseudouridine in viral RNA was recently shown to attenuate the activation of the RIG-I innate signaling pathway (33)."