IndraLab

Statements

TNF increases the amount of CD4. 6 / 7
| 6
reach
"Conversely, neither LPS nor TNF-alpha and IL-1 beta were able to modulate surface CD4 expression on quiescent or phytohaemagglutinin (PHA)-activated lymphocytes."
7586702
reach
"This down-regulation of CD4 expression by LPS, TNF-alpha, and IL-1 beta occurs at the level of transcription."
7586702
reach
"We also found that TNF-a could induce and maintain CD4 expression in L4E cells, although this is not the factor produced by SO stroma (32)."
7720091
reach
"TNF and IFN-gamma, alone or in combination, did not cause any significant change of CD4 mRNA expression in HL-60 cells, thus indicating that decrease of surface CD4, which accompanies differentiation with these cytokines, is likely due to alterations of the CD4 protein synthesis and/or transport to the plasma membrane."
1628901
reach
"We examined the hypothesis that one of the pro inflammatory cytokines, tumour necrosis factor-alpha (TNF-alpha), could induce expression of the adhesion molecule CD4 on human eosinophils."
8690465
reach
"Treatment of cultures with recombinant cytokines given at concentrations in the range of those induced by HIV-1 indicated that IL-6 and TNF alpha caused an increase of : i) CD4 expression, ii) HIV absorption to uninfected cells, and iii) release of infectious virions by infected cells."
8279951