IndraLab

Statements


USP39 increases the amount of EGFR. 3 / 4
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"Silencing of USP39 inhibited the expression of EGFR 3 '-end, and presented a remarkable block to the maturation of EGFR mRNA, suggesting that silencing of USP39 decreased the transcriptional elongation and maturation of EGFR mRNA."

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"Microarray analysis suggested that knockdown of USP39 caused a reduced expression of EGFR."

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"In prostate cancer, USP39 promotes cell proliferation by modulating mutations at the K6, K16, K29, K51, and K73 loci of SUMO and regulating EGFR mRNA transcription [47, 91]."