IndraLab

Statements


USP9X inhibits TGFB. 3 / 3
| 3

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"Where indicated, control cells were supplemented with 5 muM SB431542 (Tocris) in the medium to quench autocrine TGFbeta signaling.For FAM knockdown, the sequences of the siRNA were as follows : # 1 : [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Depletion of FAM or Smad4 abolished TGFbeta induced migration."

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"Thus loss of USP9x can increase TGFbeta signaling, potentially contributing to tumorigenesis."