IndraLab

Statements

USP29 inhibits inflammatory response. 8 / 8
| 8
reach
"In conclusion, these results indicate that USP29 knockout accelerates hepatic steatosis, inflammation and fibrosis induced by a HFHC diet."
39355870
reach
"Intriguingly, USP29 overexpression obviously attenuated hepatic steatosis, inflammation, collagen deposition and liver injury (Supplementary Fig. 4H–K)."
39355870
reach
"Thus, our results suggest that USP29 attenuates hepatic I/R injury by inhibiting the inflammatory response and apoptosis.We performed an RNA-sequencing (RNA-Seq) analysis of liver tissues from USP29 knockout mice and controls with I/R injury after 3h, and the results of the KEGG signaling pathway enrichment analysis showed that the MAPK signaling pathway was the most affected after USP29 knockout."
37304282
reach
"Hepatic steatosis, inflammation and fibrosis were significantly exacerbated by USP29 deletion and relieved by USP29 overexpression."
39355870
reach
"The above results suggest that USP29 deficiency promotes local inflammation and hepatocyte apoptosis to exacerbate hepatic I/R injury."
37304282
reach
"USP29 overexpression inhibits hepatic injury, inflammatory response, and apoptosis."
37304282
reach
"USP29 knockout accelerates hepatic steatosis, inflammation and fibrosis induced by a HFHC diet."
39355870
reach
"Specifically, diet-induced hepatic steatosis, inflammation and fibrosis were significantly exacerbated by USP29 deletion and relieved by USP29 overexpression."
39355870