IndraLab

Statements

Fenofibrate inhibits KCNQ1. 2 / 3
| 1 1
eidos
"Fenofibrate ( PPARalpha activator ) has previously been shown to inhibit KV7.1 ( IC50 of 1muM ) and thus represents validation that our screen is able to retrieve this compound ( 32 ) ."
31332533
reach
"Membrane permeabilization experiments on T84 cells indicated that fenofibrate inhibits basolateral cAMP stimulated K (+) channels (putatively KCNQ1 and KCNE3) without affecting Ca (2+)-stimulated K (+) channel activity, whereas clofibrate inhibits both K (+) pathways."
17916649