IndraLab

Statements

OTUD3 increases the amount of IL6. 4 / 4
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"Overexpression of OTUD3 in THP-1 cells promoted HSV-1-induced IFNβ , ISG56 , CXCl10 , and IL6 expression steadily with the increase in infection time ( Figure 5 A ), in contrast to its impact on RNA v[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, the reconstitution of Otud3 , but not Otud3 (C76A), in Otud3 -deficient MEFs induced the transcription of the downstream genes Ifnb1 , Isg56 , Cxcl10 , and Il6 upon HSV-1 infection ( Figu[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Moreover, knockdown of OTUD3 also suppressed ISD45-induced IFNβ , ISG56 , CXCl10 , and IL6 expression ( Figure 5 C)."
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"Additionally, knockdown of OTUD3 in HFF cells enhanced SeV- and EMCV-induced IFNB1 and IL6 expression, whereas the ectopic expression of OTUD3 suppressed the SeV- and EMCV-induced IFNB1 and IL6 expres[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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