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USP2 activates NEDD4L. 2 / 2
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"However, coexpression of USP2 together with Nedd4-2 and KCNQ1 augments the binding efficiency of Nedd4-2, indicating that either both USP2-45 and USP-69 stabilize the binding to the KCNQ1 protein or N[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Interestingly, Nedd4-2 coimmunoprecipitation with wild-type KCNQ1 was increased when USP2 was coexpressed, suggesting that USP2 may augment the binding of Nedd4-2 to the channel complex."