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KCNMA1 inhibits Blood Pressure. 2 / 2
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"Interestingly, by the same measure, vascular BK channel deficiency tended to reduce sympathetic and increase parasympathetic drive of BP and HR in both control and high-fat fed mice."
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"[XREF_BIBR - XREF_BIBR] More recent work in high-fat fed rats and mice indicated that impaired BK channel function contributes to elevated BP through increased tone in resistance arteries, and that reduced BK beta1-subunit expression plays a major role in obesity associated vascular dysfunction."
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