IndraLab

Statements


COPS8 increases the amount of COPS5. 2 / 2
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"The decrease in CSN8 suppressed protein levels of CSN3, CSN5 and CSN7 but had little effect on CSN1, CSN2, CSN4, and CSN6 protein levels (XREF_FIG)."

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"Mechanistically, CCL5 leads to the formation of the nuclear factor κρρa p65/STAT3 complex, which binds to the COP9 signal 5 (CSN5) promoter to upregulates CSN5 gene expression."