IndraLab

Statements


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sparser
"The intact chondroitin sulfate form of serglycin, but not free GAG chains isolated from the molecule, binds effectively to fibronectin, collagen , and CD44 ."

sparser
"CD44 is a cell surface receptor for hyaluronic acid and binds to collagen, fibronectin and chondroitin sulfate [ xref ]."

sparser
"Binding of HA to the broadly distributed cell surface glycoprotein CD44 as well as interactions of CD44 with collagen and fibronectin confer cell–matrix contacts and the expression of one human CD44 i[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"These findings indicate that CD44 deletion is not sufficient to increase HA accumulation post-wounding, and further studies need to be conducted to understand the regulation of HA synthesis, signaling via other receptors, and interaction with additional CD44 ligands such as fibronectin and collagen during cutaneous wound healing."