IndraLab

Statements


UCHL1 deubiquitinates HDAC6. 1 / 1
1 |

"By reducing the production of lysine (K63)-linked ubiquitin chains, <span class="match term0">UCH-L1</span> inhibition decreases <span class="match term1">HDAC6</span> deacetylase activity and attenuates the interaction of <span class="match term1">HDAC6</span> and tau protein, finally leading to tau aggresome formation impairment. "