IndraLab

Statements

Azithromycin inhibits JUN. 3 / 3
| 3
reach
"Azithromycin prevents the transcription factors nuclear factor-kappa B or activator protein-1, which may be the reason behind their inhibition of the synthesis of various pro-inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8, and tumor necrosis factor-alpha [25]."
39085799
reach
"Conversely, it has been shown that azithromycin inhibits the binding of activator protein-1, nuclear factor of activated T cells, and interferon consensus sequence binding protein to the DNA binding site in the IL-12p40 promoter, and down regulation of TLR-4 receptor by azithromycin has also been reported, and these could represent important mechanisms contributing to the anti-inflammatory effects of azithromycin."
25505605
reach
"3.3 Azithromycin Inhibits the Activities of TGF-beta/Smad and JNK/C-Jun Signaling Pathways in Mouse Pulmonary Fibrosis."
34803671