IndraLab

Statements

USP22 binds KDELR1. 5 / 5
| 5
sparser
"USP22 Interacts with KDELR1 and Stabilizes KDELR1 Expression via Deubiquitination."
39101247
sparser
"We confirmed the interaction between USP22 and KDELR1 using molecular docking simulations and co‐IP assays (Figure  xref )."
39101247
sparser
"These results confirmed that the C19 ubiquitin‐specific peptidase domain of USP22 was the dominant mediator of the interaction between USP22 and KDELR1."
39101247
sparser
"The interaction between USP22 and KDELR1 was validated using a PLA assay (Figure  xref )."
39101247
sparser
"Therefore, we hypothesized that the USP22‐KDELR1 axis regulates the invadopodia process to drive LUAD metastasis."
39101247