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USP18 inhibits immune response. 3 / 3

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"USP2b, USP3, USP18, USP25, UL36USP and HAUSP play a role of antivirus; while USP4, USP13, USP15 and USP17 negatively regulate antiviral immune response."

26713535

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"Ectopic expression of USP18 in tumor cells suppressed tumorigenesis and antitumor immune response whereas inhibition of USP18 expression promoted tumorigenesis and immunosurveillance."

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"USP18 enzymatic function typically attenuates the immune response by removing interferon-stimulated gene 15 (ISG15) from protein substrates."

37002195

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USP18 inhibits immune response. 3 / 3

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