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USP8 decreases the amount of BACE1. 2 / 2

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"Moreover, USP8 depletion increased BACE1 ubiquitination, promoted BACE1 accumulation in the early endosomes and late endosomes and lysosomes, and decreased levels of BACE1 in the recycling endosomes."

27302062

➶

reach

"Studies have shown that RNAi mediated depletion of USP8 increased BACE1 ubiquitination on Lys 501, promoted BACE1 accumulation in the early endosomes and late endosomes and lysosomes, and decreased levels of BACE1 in the recycling endosomes."

28469554

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IndraLab

Statements

USP8 decreases the amount of BACE1. 2 / 2

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