IndraLab

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OTUD5 activates E3_Ub_ligase. 2 / 2

| 2

reach

"Given that TRAF3 may be dispensable for RIG-I signalling XREF_BIBR, it can not be excluded, however, that DUBA also targets other E3 ligases like TRAF2, 5 and 6."

24375678

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reach

"Mechanistically, OTUD5 promotes K63-linked polyubiquitination of alpha-Syn independent of its deubiquitinating enzyme activity and mediates its endolysosomal degradation by recruiting the E3 ligase neural precursor cell expressed developmentally downregulated 4 (NEDD4)."

39721018

INDRA sources:

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IndraLab

Statements

OTUD5 activates E3_Ub_ligase. 2 / 2

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