IndraLab

Statements


| 4

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"Furthermore, blunted crystal phagocytosis was associated with attenuated induction of IL-1β expression and production by CD44 deficient macrophages."

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"For mRNA we observed over-representation in Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA (FDR < 5.9 × 10 −6 , CLEC7A/inflammasome pathway (FDR < 3.0 × 10 −3 Interleukin-4 and Interleukin-13 signaling (FDR < 0.026) -the genes involved include CD44 and IL1B, that are associated with monocyte aggregation, and FCGR2B and SAMSN1 that are involved in negative regulation of B-cell proliferation."
| DOI

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"For mRNA we observed over-representation in Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA (FDR), CLEC7A/inflammasome pathway (FDR), Interleukin-4 and Interleukin-13 signaling (FDR)—the genes involved include CD44 and IL1B, that are associated with monocyte aggregation, and FCGR2B and SAMSN1 that are involved in negative regulation of B-cell proliferation."
| PMC

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"Despite lack of increased expression of CD44, or expression of novel splice variants, we have demonstrated increased binding of exogenous fl-HA by CD44 following stimulation with either IL-1β or 25mM [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"