IndraLab

Statements


COPS6 inhibits CTSL. 5 / 5
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"CSN6-mediated CTSL up-regulation was decreased by Rapamycin."

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"In summary, our study showed that down- regulation of CSN6 inhibits invasion via autophagic degradation of CTSL in CC."

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"CSN6 could suppress the degradation of CTSL, then facilitated the migration and invasion of CC cells."

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"In contrast, overexpression of CSN6 decreased the turnover rate of CTSL (Fig. 8D)."

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"Taken together, we concluded that CSN6 might promote the migration and invasion of cervical cancer cells by inhibiting autophagic degradation of CTSL and serve as a potential gene therapy target for the treatment of CC metastasis."